ncRNA name | TLR2 siRNA |
ncRNA Category | siRNA |
Disease name | fungal keratitis |
Species | Homo sapiens |
Tissues/Cell_line | telomerase-immortalized human stroma fibroblasts (THSF) |
Methods | siRNA transfection, immunofluorescence analysis, RT-PCR, Western blot, qPCR |
Expression pattern | associated |
Functional description | THSF transfected with TLR2-siRNA plasmid exhibited a reduced level of TLR2 when compared with the control cells transfected with empty plasmid. F. solu-stimulated IL-10 production by transfected THSF was severely impaired, while IL-1beta production was partially inhibited. |
PubMed ID | 18195725 |
Year | 2008 |
Title | Toll-like receptor 2 mediates the induction of IL-10 in corneal fibroblasts in response to Fusarium solu. |
Drug-related ncRNA | NO |
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